45
13
10
5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14176 | Aleglitazar | RO0728804,R1439 | PPAR |
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes. | |||
T77125 | Otilimab | GSK 3196165,MOR103 | CSF-1R |
Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking... | |||
T77019 | Garetosmab | REGN 2477 | TGF-beta/Smad |
Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dyspl... | |||
T60951 | Molnupiravir | EIDD-2801,Lagevrio,MK-4482 | SARS-CoV , Influenza Virus |
Molnupiravir (MK-4482) (EIDD-2801) is a prodrug of the ribonucleoside analog EIDD-1931 which is orally bioavailable. Molnupiravir can be used in COVID-19, seasonal and pandemic influenza research that has broad spectrum ... | |||
T63098 | SARS-CoV-2 Mpro-IN-2 | ||
SARS-CoV-2 MPro-IN-2 is a selective, low cytotoxic, non-covalent Mpro inhibitor with an IC50 value of 0.40 μM. SARS-CoV-2 Mpro-IN-2 showed good anti-SARS-CoV-2 effect with EC50 value of 1.1 μM. SARS-CoV-2 Mpro-IN-2 can b... | |||
T76781 | Itolizumab | EQ-001 | Others |
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti... | |||
T6783 | BI-7273 | Epigenetic Reader Domain | |
BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell. | |||
T9025 | KY19382 | 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051 | Others , GSK-3 , Wnt/beta-catenin |
KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It... | |||
T124358 | Deferoxamine | Deferoxamine B,Desferrioxamine B | Apoptosis , Antioxidant , HIF , Autophagy |
Deferoxamine(Desferrioxamine B) is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may imp... | |||
T72501 | CYP4A11/CYP4F2-IN-1 | P450 | |
CYP4A11/CYP4F2-IN-1 is a cytochrome P450 (CYP) 4A11 and CYP4F2 inhibitor. CYP4A11/CYP4F2-IN-1 can be used to study kidney diseases and cardiovascular and cerebrovascular diseases. | |||
T8388 | Vonoprazan | TAK-438 (free base) | Proton pump |
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis | |||
TP1501L | CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base) | MMP | |
CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, an... | |||
T0242 | Sitagliptin | MK0431 | Proteasome , DPP-4 , Autophagy |
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedion... | |||
T37239 | (±)19(20)-EpDTE | ||
(±)19(20)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid . It is formed via cytochrome P450 (CYP) metabolism of DPA and can be further metabolized to (±)19(20)-DiHDTE by epoxide hydrolase. | |||
T63837 | RET-IN-19 | ||
RET-IN-19 is a potent inhibitor of RET and exhibits anticancer effects on RET-wt (IC50: 6.8 nM) and RET V804M (IC50: 13.51 nM).RET-IN-19 can be used to study non-small cell lung cancer (NSCLC). | |||
T63660 | Anti-inflammatory agent 19 | ||
Anti-inflammatory agent 19 inhibits NO (IC50: 36.00 μM). anti-inflammatory agent 19 exhibits an inhibitory effect on HMGB1-induced late inflammatory responses. anti-inflammatory agent 19 can be used to study late inflamm... | |||
T63315 | IRAK4-IN-19 | ||
IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 4.3 nM).IRAK4-IN-19 inhibits LPS-induced IL23 production in THP and DC cells and suppresses the development of arthritis in a... | |||
T63181 | SARS-CoV-2-IN-32 | ||
SARS-CoV-2-IN-32 is a COVID-19 inhibitor. SARS-CoV-2-IN-32 exhibits good binding affinity (-8.8 Kcal/mole) for the COVID-19 major protease (Mpro) (PDB ID: 6LU7) and has anti-proliferative effects on cancer cells. IN-32 c... | |||
T63628 | AChE-IN-19 | ||
AChE-IN-19 is a potent inhibitor of AChE (IC50: 0.56 μM) and also exhibits inhibition of Aβ aggregation. aChE-IN-19 exhibits neuroprotective effects and is virtually non-toxic to SH-SY5Y cells. aChE-IN-19 can be used to ... | |||
T63694 | SARS-CoV-2-IN-33 | ||
SARS-CoV-2-IN-33 is an inhibitor of COVID-19. SARS-CoV-2-IN-3 exhibits good binding affinity (-8.0 Kcal/mole) for COVID-19 major protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 exhibits good anti-proliferative effects o... | |||
T63302 | BRD4 Inhibitor-19 | ||
BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma. | |||
T63122 | CBP/p300-IN-19 | ||
CBP/p300-IN-19 is a potent inhibitor of p300/CBP HAT, which can act on P300-HAT (IC50: 1.4 μM), CBP-HAT (IC50: 1.4 μm), 2.2 μM), PCAF (IC50>100 μM), and Myst3 (IC50>100 μM). CBP/p300-IN-19 has anti-tumor activity. | |||
T63490 | CDK9-IN-19 | ||
CDK9-IN-19 is a selective and potent CDK9 inhibitor (IC50: 2.0 nM). CDK9-IN-19 exhibits good anti-proliferative activity in cancer cells, moderate pharmacokinetic properties and low hERG inhibition. CDK9-IN-19 significan... | |||
T63709 | Nezulcitinib | ||
Nezulcitinib (TD-0903) is an inhaled, lung-selective inhibitor of pan-Janus kinase (JAK) that can be used to study COVID-19-associated acute lung injury and impaired oxygenation. | |||
T79663 | E07 aptamer | SARS-CoV | |
SARS-CoV-2 nsp14-IN-4 (Compound 12q) is a selective inhibitor of the SARS-CoV-2 nsp14 methyltransferase with an IC50 of 19 ± 2.5 nM. Lacking a zwitterionic character, it can penetrate cells and is useful in research on C... | |||
T63023 | PTP1B-IN-19 | ||
PTP1B-IN-19 (Compound 43) is a promising selective benzimidazole derivative as a protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 23.3 μM).PTP1B-IN-17 can be used to study type 2 diabetes. | |||
T63473 | Anti-inflammatory agent 18 | ||
Anti-inflammatory agent 18 inhibits NO activity (IC50: 15.94 μM) and has an inhibitory effect on the late inflammatory response induced by HMGB1 and can be used to study late inflammatory diseases such as coronavirus dis... | |||
T62248 | SARS-CoV-2 nsp13-IN-6 | ||
SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on ssDNA+ATPase (IC50: 27 μM) and ssDNA-ATPase (IC50: 33 μM). nsp13-IN-6 can be used in anti-COVID-19 st... | |||
T64283 | Pacritinib hydrochloride | ||
Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM). Pacritinib hydrochloride can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis ... | |||
T63615 | SARS-CoV-2 nsp13-IN-5 | ||
SARS-CoV-2 nsp13-IN-5 is a potent inhibitor of SARS-CoV-2 nsp13, capable of acting on ssDNA+ATPase (IC50: 50 μM) and ssDNA-ATPase (IC50: 55 μM). SARS-CoV-2 nsp13-IN-5 can be used in anti-COVID-19 studies. | |||
T64273 | Nampt-IN-10 TFA | ||
Nampt-IN-10 TFA (compound 4) is a phosphoribosyltransferase (NAMPT) inhibitor with cellular efficacy against A2780 (IC50: 5 nM) and CORL23 (IC50: 19 nM). The Nampt-IN-10 TFA can be used as a non-antimitotic payload for A... | |||
T62958 | SARS-CoV-2-IN-31 | ||
SARS-CoV-2-IN-31 is a potent inhibitor of COVID-19. SARS-CoV-2-IN-31 shows excellent to mild activity (IC50: 28.84-38.36 μM) against a variety of cancer cell lines. SARS-CoV-2-IN-31 can be used in cancer research. | |||
T62236 | Steroid sulfatase/17β-HSD1-IN-3 | ||
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 can be used to study endometriosis and ... | |||
T35468 | (±)19(20)-EDP Ethanolamide | ||
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). It is produced through direct epoxygenation of docosahexaenoyl et... | |||
T72145 | Montelukast dicyclohexylamine | MK0476 dicyclohexylamine | |
Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits a... | |||
T60488 | Ganciclovir hydrate | ||
Ganciclovir (BW 759) hydrate is a nucleoside analogue that is an orally active antiviral agent with anti-cytomegalovirus activity. Ganciclovir hydrate is also active against members of the herpes group and some other DNA... | |||
TMIH-0601 | Vonoprazan-d3 | ||
Vonoprazan-d3 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden... | |||
TMIH-0602 | Vonoprazan-d4 | ||
Vonoprazan-d4 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden... | |||
T37154 | 7-Methylguanosine 5'-diphosphate sodium | ||
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1]. | |||
T37605 | D-DOPA | ||
D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, i... | |||
T64692 | AMY-101 acetate | ||
Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe... | |||
T37880 | OPC-167832 | ||
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16... | |||
T36722 | Deltorphin II (trifluoroacetate salt) | ||
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [3... | |||
T37861 | Talabostat | ||
Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 ... | |||
T37582 | Ganglioside GM1 Mixture (ovine) (ammonium salt) | ||
Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched i... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN7123 | Enmein, 13-deoxy-19-hydroxy-, (19R)- | Others | |
Enmein, 13-deoxy-19-hydroxy-, (19R)- is an Enmein-type diterpene derivative and can be used in the preparation of antitumor drugs. | |||
T8070 | Nonadecanoic acid | Others | |
Nonadecanoic acid is a long saturated fatty acid found in ox fats and vegetable oils, and in Staphylococcus. It can be used as a phermone by certain insects. | |||
T83570 | (23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol | ||
(23E)-5β,19-epoxycucurbita-6,23,25(26)-triene-3β-ol, a cucurbitane triterpenoid, can be isolated from the seeds of Momordica charantia L. [1]. | |||
TN6493 | 19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene | ||
19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene is a natural product of Pinus, Pinaceae. The catalog number is TN6493 and the CAS number is 1011714-20-7. 19-O-beta-D-carb... | |||
TN3948 | Ent-3Beta-Angeloyloxykaur-16-en-19-oic acid | Others | |
ent-3Beta-Angeloyloxykaur-16-en-19-oic acid is a natural product of Wedelia, Asteraceae. The catalog number is TN3948 and the CAS number is 74635-61-3. ent-3Beta-Angeloyloxykaur-16-en-19-oic acid can be used as a referen... | |||
TN2700 | 2,3-dihydrosciadopitysin | Others | |
2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard. | |||
TN3939 | Ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid | Others | |
ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid is a natural product of Xanthium, Asteraceae. The catalog number is TN3939 and the CAS number is 55483-24-4. ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid can be used a... | |||
TN3269 | 8,9-Didehydro-7-hydroxydolichodial | Others | |
8,9-Didehydro-7-hydroxydolichodial is a natural product of Patrinia, Valerianaceae. The catalog number is TN3269 and the CAS number is 97856-19-4. 8,9-Didehydro-7-hydroxydolichodial can be used as a reference standard. | |||
TN3069 | 4beta-Carboxy-19-nortotarol | NADPH-oxidase | |
4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not genera... | |||
TN2486 | 1-(3,4-Dimethoxyphenyl)propane-1,2-diol | Others | |
β-Aflatrem is a natural product of Chloranthus, Chloranthaceae. The catalog number is TN2486 and the CAS number is 20133-19-1. β-Aflatrem can be used as a reference standard. | |||
TN3254 | 7alpha-Hydroxystigmasterol | Others | |
7alpha-Hydroxystigmasterol is a natural product of Xanthium, Asteraceae. The catalog number is TN3254 and the CAS number is 64998-19-2. 7alpha-Hydroxystigmasterol can be used as a reference standard. | |||
TN2757 | 2-Epitormentic acid | Others | |
2-Epitormentic acid is a natural product of Potentilla, Rosaceae. The catalog number is TN2757 and the CAS number is 119725-19-8. 2-Epitormentic acid can be used as a reference standard. | |||
TN5637 | 5-(Z-Heptadec-8-enyl)resorcinol | 5-(8-Heptadecenyl)-1,3-benzenediol | |
5-(Z-Heptadec-8-enyl)resorcinol is a natural product of Ardisia, Myrsinaceae. The catalog number is TN5637 and the CAS number is 52483-19-9. 5-(Z-Heptadec-8-enyl)resorcinol can be used as a reference standard. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00998 | S100A2 Protein, Human, Recombinant | Human | E. coli |
S100A2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11 kDa and the accession number is P29034. | |||
TMPY-00910 | S100A2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
S100A2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.6 kDa and the accession number is P29034. | |||
TMPJ-01270 | ZMYND19 Protein, Human, Recombinant (His) | Human | E. coli |
Human Zinc Finger MYND Domain-Containing Protein 19 (ZMYND19) is a protein that contains 1 MYND-Type Zinc Finger. ZMYND19 can be expressed by the brain, testis, placenta, heart, liver, skeletal muscle, kidney, and stomac... | |||
TMPJ-01255 | CFHR4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement factor H-related protein 4 is a protein that in humans is encoded by the CFHR4 gene. It is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are... | |||
TMPJ-00715 | FGF-19 Protein, Human, Recombinant (His) | Human | E. coli |
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 dis... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPJ-01277 | CRT2 Protein, Human, Recombinant | Human | E. coli |
Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-doma... | |||
TMPJ-01086 | CD244 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like d... | |||
TMPJ-00909 | IL-1RA Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and int... | |||
TMPY-06885 | SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His) | ||
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... |
Cat No. | Product Name | ||
---|---|---|---|
L1710 | Anti-COVID-19 Compound Library | 1133 compounds | |
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; | |||
L9230 | ReFRAME Related Library | 3210 compounds | |
A unique collection of 3210 compounds for high-throughput screening and high-content screening, | |||
L3980 | DNA Damage and Repair Compound Library Plus | 667 compounds | |
Well-chosen 667 compounds with unique structures targeting DNA damage & repair; | |||
L6720 | Anti-COVID-19 Traditional Chinese Medicine Compound Library | 1147 compounds | |
A unique collection of 1147 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening; | |||
L4700 | Immunology/Inflammation Compound Library | 4720 compounds | |
A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening. |